Most drug targets are receptors expressed on the cell surface. Approximately half of those are G protein-coupled receptors (GPCRs), a class of seven transmembrane domain receptors. GPCRs remain the most pursued drug targets by academic and pharmaceutical groups (Lagerström…
GPCR-Ligand… GPCR-Ligand Association

GLASS GPCR-Ligand Association

Aims to provide a comprehensive, manually-curated resource for experimentally…

Aims to provide a comprehensive, manually-curated resource for experimentally validated GPCR-ligand associations. A new text-mining algorithm was proposed to collect GPCR-ligand interactions from the…

GPCR-Oligomerization… GPCR-Oligomerization Knowledge Base

GPCR-OKB GPCR-Oligomerization Knowledge Base

A system that supports browsing and searching for GPCR oligomer data. Such data…

A system that supports browsing and searching for GPCR oligomer data. Such data were manually derived from the literature. While focused on GPCR oligomers, GPCR-OKB is seamlessly connected to GPCRDB,…

Human-gpDB Human-gpDB

Human-gpDB

A database which currently holds information about 713 human GPCRs, 36 human…

A database which currently holds information about 713 human GPCRs, 36 human G-proteins and 99 human effectors. The collection of information about the interactions between these molecules was done…

IUPHAR/BPS Guide to… IUPHAR/BPS Guide to PHARMACOLOGY

GtoPdb IUPHAR/BPS Guide to PHARMACOLOGY

Provides expert-curated molecular interactions between successful and potential…

Provides expert-curated molecular interactions between successful and potential drugs and their targets in the human genome. The information in the database is presented at two levels: the initial…

PDSP Ki database PDSP Ki database

PDSP Ki database

A unique resource in the public domain which provides information on the…

A unique resource in the public domain which provides information on the abilities of drugs to interact with an expanding number of molecular targets. The Ki database serves as a data warehouse for…

GPCR ontology GPCR ontology

BAO-GPCR GPCR ontology

Facilitates integration and aggregation of GPCR-targeting drugs and demonstrate…

Facilitates integration and aggregation of GPCR-targeting drugs and demonstrate its application to classify and analyze a large subset of the PubChem database. The GPCR ontology, based on previously…

G protein-coupled… G protein-coupled receptors database

GPCRDB G protein-coupled receptors database

A molecular-class information system that collects, combines, validates and…

A molecular-class information system that collects, combines, validates and stores large amounts of heterogenous data on G protein-coupled receptors (GPCRs). The GPCRDB contains data on sequences,…

gpDB gpDB

gpDB

A publicly accessible, relational database of G-proteins and their interactions…

A publicly accessible, relational database of G-proteins and their interactions with GPCRs and effector molecules. The sequences are classified according to a hierarchy of different classes, families…

GPCR Decoy Database GPCR Decoy Database

GDD GPCR Decoy Database

A G protein-coupled receptor (GPCR) ligand library (GLL) for 147 targets,…

A G protein-coupled receptor (GPCR) ligand library (GLL) for 147 targets, selecting for each ligand 39 decoy molecules, collected in the GPCR Decoy Database (GDD). Decoys were chosen ensuring a…

GPCR-LIgand DAtabase GPCR-LIgand DAtabase

GLIDA GPCR-LIgand DAtabase

A public GPCR-related chemical genomics database that is primarily focused on…

A public GPCR-related chemical genomics database that is primarily focused on the integration of information between GPCRs and their ligands. It provides interaction data between GPCRs and their…

PubChem PubChem

PubChem

A public repository for information on chemical substances and their biological…

A public repository for information on chemical substances and their biological activities. Since launched in 2004 as a component of the Molecular Libraries Roadmap Initiatives of the US National…

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