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- Caenorhabditis elegans
- Mus musculus
Publication for GlycoProtDB
Predicting the Coupling Specificity of G protein Coupled Receptors to G proteins by Support Vector Machines
[…] In this study, 124 human GPCR sequences (62, 33, and 29 sequences for Gi/o-, Gq/11-, Gs-class, respectively) were collected from the gpDB database , which were used to develop the SVM classifiers for three classes of GPCRs. Ten-fold cross-validation process was used to evaluate the performance of the proposed method, that is, nine […]
The Repertoire of Heterotrimeric G Proteins and RGS Proteins in Ciona intestinalis
[…] Multiple sequence alignment of the Ciona sequences with known orthologs picked up from the gpDB database was performed using CLUSTALX 1.8 program using the default parameters for substitution matrices and gap penalties. Manual adjustments of the alignments were made when necessary using th […]
Whole proteome identification of plant candidate G protein coupled receptors in Arabidopsis, rice, and poplar: computational prediction and in vivo protein coupling
[…] the SEVENS database  contain only GCR1 and sequences from the mildew locus o (MLO) family, although SEVENS also includes GCR2 and its two homologs. Searches of the GPCR/G-protein/effector database gpDB  did not identify any plant sequences in the GPCR category.To circumvent these problems, we have developed a combinatorial approach to identify novel GPCRs based on the direct prediction of GPC […]
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