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GPI anchor attachment prediction software tools | Post-translational modification analysis

Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-terminal residue after a proteolytic cleavage occurring at the so called…
big-Pi plant
Web

big-Pi plant

A program for the prediction of compatibility of query protein C-termini with…

A program for the prediction of compatibility of query protein C-termini with the plant GPI lipid anchor motif requirements. Validation tests show that the sensitivity for transamidase targets is…

GPI-SOM
Desktop
Web

GPI-SOM

A Kohonen self-organizing map was developed that predicts GPI-anchored proteins…

A Kohonen self-organizing map was developed that predicts GPI-anchored proteins with high accuracy. In combination with SignalP, GPI-SOM was used in genome-wide surveys for GPI-anchored proteins in…

big-Pi…
Web

big-Pi predictor

Evaluates the degree of presence of the C-terminal sequence signal in a query…

Evaluates the degree of presence of the C-terminal sequence signal in a query proprotein sequence based on sequence properties extracted from a learning set. big-Pi predictor allows large-scale…

PredGPI
Web

PredGPI

A prediction system for GPI-anchored proteins. PredGPI is based on a support…

A prediction system for GPI-anchored proteins. PredGPI is based on a support vector machine (SVM) for the discrimination of the anchoring signal, and on a Hidden Markov Model (HMM) for the prediction…

FragAnchor
Web

FragAnchor

A computational system based on the tandem use of a Neural Network predictor…

A computational system based on the tandem use of a Neural Network predictor and a Hidden Markov Model predictor. The Neural Network is used to select the potential GPI-anchored sequences and the…

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