A package to execute BLAST (Basic Local Alignment Search Tool). GPU-BLAST aligns query sequences against those present in a selected target database. This software can realize protein alignment according to blastp algorithm (comparaison between protein sequences only). It uses the source code of the NCBI-BLAST but also GPU to accelerate execution. In comparison to the sequential NCBI-BLAST, the speedups achieved by GPU-BLAST range mostly between 3 and 4.