GR Calculator statistics

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Citations per year

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Drug sensitivity Drug resistance

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GR Calculator specifications

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Information

Unique identifier	OMICS_19061
Name	GR Calculator
Interface	Web user interface
Restrictions to use	None
Input format	TSV, CSV
Computer skills	Basic
Stability	Stable
Maintained	Yes

Maintainer

Peter Sorger <>

Additional information

GRcalculator: an online tool for calculating and mining drug response data http://doi.org/10.6084/m9.figshare.4244408.v1

Publication for GR Calculator

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs.

2016 Nat Methods

PMCID: 4887336

PMID: 27135972

DOI: 10.1038/nmeth.3853

GR Calculator in publication

A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

PMCID: 5951639

PMID: 29655704

DOI: 10.1016/j.cels.2018.03.012

[…] identify cells based on digital-phase contrast images and to count total cell numbers within four fields of view. growth rate (gr) values were computed, and sigmoid curves were fit using the online gr calculator (). the gr value represents cell count relative to dmso control, adjusted for the cell line’s growth rate., to determine whether a perturbation or a group of perturbations significantly […]

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GR Calculator institution(s)

HMS LINCS Center, Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA, USA

GR Calculator funding source(s)

Supported by grants U54-HL127365 and P50-GM107618 and by a fellowship from the Swiss National Science Foundation (P300P3_147876).

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