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Provides score-based prediction of potential cleavage sites for the caspases 1-9 and granzyme B including an estimation of the fragment size. GraBCas offers an easy to use, concise user interface in register card format. The design of GraBCas specifically acknowledged the high variability of cleavage site recognition sequences. We validated our tool by scoring known substrates and demonstrated its usefulness for protein sequence analysis.

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GraBCas classification

GraBCas specifications

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GraBCas distribution


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Department of Human Genetics, Medical School, University of Saarland Homburg/Saar, Germany; Center for Bioinformatics, University of Saarland, Saarbrücken, Germany

Funding source(s)

A grant of the Center of Bioinformatics/Saarbrücken supported by the Deutsche Forschungsgemeinschaft; a grant from the Deutsche Krebshilfe (10-1966-Me4)

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