Provides a batch tool for user. GsNetCom is a web-based toolkit to measure the functional association between two gene sets. It is based on a method called corrected cumulative rank score(CCRS) which quantifies the functional relationship between two gene sets considering functional communication and physical interaction of genes. It presents an annotation tool, FUNC NOTE, for gene set based on protein complex data. GsNetCom utilized corrected cumulative rank score (CCRS) to reflect the functional association between the query gene set and known complexes and obtained a ranked complex list which shown the potential function of the query gene set.
College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China; Bioinformatics Center, Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
GsNetCom funding source(s)
This work was supported by The National Natural Science Foundation of China (Grant nos 30871394 and 61073136); the National High Tech Development Project of China; the 863 Program (Grant no. 2007AA02Z329); National Science Foundation of Heilongjiang Province (Grant no. QC2009C23); the Science Foundation of Educational Commission of Heilongjiang Province (Grant no. 11551233).