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GUDMAP specifications

Information


Unique identifier OMICS_04093
Name GUDMAP
Alternative name GenitoUrinary Development Molecular Anatomy Project
Restrictions to use None
Maintained Yes

Taxon


  • Rodents
    • Mus musculus

Maintainer


  • person_outline Simon D. Harding

Publication for GenitoUrinary Development Molecular Anatomy Project

GUDMAP citations

 (7)
library_books

Identification of novel candidate genes for 46,XY disorders of sex development (DSD) using a C57BL/6J YPOS mouse model

2018
PMCID: 5789682
PMID: 29378665
DOI: 10.1186/s13293-018-0167-9

[…] ous or damaging), availability of literature (some weight was given to genes with known functions), and gonadal cell-specific expressivity using GenitoUrinary Developmental Molecular Anatomy Project (GUDMAP) data [] (preference was given to genes expressed in male-typical cells).Using the abovementioned filtering criteria, we identified 15 novel candidate sex developmental genes, variants in which […]

library_books

A homozygous missense variant in VWA2, encoding an interactor of the Fraser complex, in a patient with vesicoureteral reflux

2018
PLoS One
PMCID: 5774751
PMID: 29351342
DOI: 10.1371/journal.pone.0191224

[…] e (Mouse genome informatics, http://www.informatics.jax.org) to date. The identified phenotype however, does not include malformations of the renal or urinary system (MGI ID: 97490). Data obtained by Gudmap (GenitoUrinary Molecular Anatomy Project, http://www.gudmap.org) revealed, that 2 (Atp10d and Nell2) out of the 5 identified genes/proteins do not reach significant expression levels in the mur […]

library_books

Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts

2017
eLife
PMCID: 5484618
PMID: 28577314
DOI: 10.7554/eLife.24265.044

[…] ound 843 differentially expressed genes in a comparison of EIIA-Cre;Tfcp2l1f/f knockout and Tfcp2l1f/f control P1 mouse kidneys (Affymetrix Microarrays analyzed by limma, n = 3, p<0.05). According to GUDMAP, the comprehensive genitourinary development database (, www.gudmap.org), our analysis showed that 62% of downregulated genes were expressed either by UB, cortical or medullary collecting ducts […]

library_books

Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1 mutant mice

2015
PMCID: 4527280
PMID: 26035382
DOI: 10.1242/dmm.018523

[…] kidney-compartment-specific genome-wide expression patterns as they were generated (via microarray and RNA-seq analysis of micro-dissected and FACS-sorted cell populations) and made available by the GUDMAP project (). These data provide expression signatures of each compartment in the developing kidney, even if the genes that make up this signature are not unique for this compartment. Note that, […]

library_books

Identification of Novel Markers of Mouse Fetal Ovary Development

2012
PLoS One
PMCID: 3406020
PMID: 22844512
DOI: 10.1371/journal.pone.0041683

[…] Primer design and riboprobe generation has been described in detail previously and is available on the GUDMAP website (http://www.gudmap.org/Research/Protocols/Little.html). In brief, microarray probe sets of the Affymetrix 430.2 were mapped to FANTOM3 cDNA clones set and mapped to the mouse genome (mm […]

library_books

Organic Anion and Cation SLC22 “Drug” Transporter (Oat1, Oat3, and Oct1) Regulation during Development and Maturation of the Kidney Proximal Tubule

2012
PLoS One
PMCID: 3396597
PMID: 22808265
DOI: 10.1371/journal.pone.0040796

[…] Microarray data for the s-shaped body and proximal tubule, published previously , , were downloaded from the GenitoUrinary Database Molecular Anatomy Project (GUDMAP) database website (www.gudmap.org). The data were analyzed using Genespring GX 11.5.1 (Agilent). Comparisons were made by T-test, using a FDR of 0.05. The in vivo and ex vivo gene lists were co […]

Citations

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GUDMAP institution(s)
MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK

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