GWAS analysis steps

Genome-wide association studies (GWASs) have been heralded as a major advance in biomedical discovery, having identified ~2,000 robust associations with complex diseases since 2005.Source text:(Manolio, 2013) Bringing genome-wide association findings into clinical use. Nat Rev…

Genome-wide association analysis software tools and databases

Most Recent Tools

EpiMODE
Desktop

EpiMODE epistatic MOdule DEtection

Takes advantage of a Bayesian model with a properly designed Gibbs sampling…

Takes advantage of a Bayesian model with a properly designed Gibbs sampling strategy to facilitate the detection of epistatic modules. It was confirmed via extensive simulation studies that epiMODE…

MAPIT
Desktop

MAPIT MArginal ePIstasis Test

Estimates and tests its marginal epistatic effect, the combined epistatic…

Estimates and tests its marginal epistatic effect, the combined epistatic effect between the examined variant and all other variants. By modeling and inferring the marginal epistatic effects, MAPIT…

PLATO
Desktop
rqt
Desktop

rqt

Offers gene-level genome-wide association study (GWAS) meta-analysis. The rqt…

Offers gene-level genome-wide association study (GWAS) meta-analysis. The rqt package can be easily included into bioinformatics pipeline or used as stand-alone. The workflow of gene-level…

Most Popular Tools

PLINK
Desktop

PLINK

A free, open-source whole genome association analysis toolset, designed to…

A free, open-source whole genome association analysis toolset, designed to perform a range of basic, large-scale analyses in a computationally efficient manner. The focus of PLINK is purely on…

CADD
Desktop

CADD Combined Annotation Dependent Depletion

Scores the deleteriousness of single nucleotide variants as well as…

Scores the deleteriousness of single nucleotide variants as well as insertion/deletions variants in the human genome. CADD integrates many diverse annotations into a quantitative score. The basis of…

i-GSEA4GWAS
Web

i-GSEA4GWAS improved GSEA for GWAS

A web-based resource for analysis of GWAS data to identify pathways/gene sets…

A web-based resource for analysis of GWAS data to identify pathways/gene sets correlated to certain traits by implementing an improved Gene Set Enrichment Analysis (i-GSEA) approach. i-GSEA4GWAS aims…

PANOGA
Web

PANOGA Pathway and Network Oriented GWAS Analysis

A web server for post-genome-wide associatio analysis. PANOGA supports pathway…

A web server for post-genome-wide associatio analysis. PANOGA supports pathway and network-oriented SNP–phenotype association analysis in a single system without requiring any additional manual…

Curators for GWAS analysis

  • Seraya Maouche's avatar image Seraya Maouche's country flag
    Seraya Maouche
    TBi Scientific, Paris, France
  • Shannon EK Joslin's avatar image Shannon EK Joslin's country flag
    Shannon EK Joslin
    University of California, Davis
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