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GWASrap specifications

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Unique identifier OMICS_12452
Name GWASrap
Interface Web user interface
Restrictions to use None
Input format Plink-like format: Chromosome, dbSNP Id, Position, P-value. Variants Coordinates: Chromosome, Position, P-value. Single SNP Id: dbSNP Id, P-value.
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Mulin Jun Li <>

Publication for GWASrap

GWASrap citations

 (2)
library_books

Long noncoding RNA LINC00305 promotes inflammation by activating the AHRR NF κB pathway in human monocytes

2017
PMCID: 5385552
PMID: 28393844
DOI: 10.1038/srep46204

[…] statistics from various resources. we then selected candidate variants located in the non-coding regions to identify disease-associated loci. using an annotation-based effect additive method (gwasrap), we extracted the atherosclerosis gwas snps and identified putative causal variants associated with the original gwas signals. briefly, for a given variant, we combined the gwas summary […]

library_books

New Variants Including ARG1 Polymorphisms Associated with C Reactive Protein Levels Identified by Genome Wide Association and Pathway Analysis

2014
PMCID: 3999194
PMID: 24763700
DOI: 10.1371/journal.pone.0095866

[…] error rate of 0.05 in 2-tailed test. the study had 90% power to detect association of a variant with a maf = 0.02 and an effect size of 0.1 for additive model., snp prioritization was performed via gwasrap (http://jjwanglab.org/gwasrap) . this tool generates a re-prioritized genetic variant list by combining the original statistical value and variant prioritization score. the 13,345 gwas snps […]


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GWASrap institution(s)
Department of Biochemistry, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China; Shenzhen Institute of Research and Innovation, The University of Hong Kong, Shenzhen, Guangdong, China; Centre for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China; Department of Psychiatry, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China; The State Key Laboratory in Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, China
GWASrap funding source(s)
This study was supported by grants from the Research Grants Council (781511M, 778609M, N_HKU752/10, AoE M-04/04), Food and Health Bureau (10091262) of Hong Kong, and The University of Hong Kong Strategic Research Theme on Genomics.

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