Hal statistics

info info

Citations per year

Number of citations per year for the bioinformatics software tool Hal

Tool usage distribution map

This map represents all the scientific publications referring to Hal per scientific context
info info

Associated diseases


Popular tool citations

chevron_left Phylogenetic inference Bioinformatics workflows Tree comparison chevron_right
Want to access the full stats & trends on this tool?


Hal specifications


Unique identifier OMICS_17820
Name Hal
Software type Pipeline/Workflow
Interface Command line interface
Restrictions to use None
Input format FASTA
Operating system Unix/Linux
Programming languages Perl
License GNU General Public License version 2.0
Computer skills Advanced
Stability Alpha
BioPerl formatdb, BLASTALL, Gblocks, ProtTest
Maintained Yes




No version available


  • person_outline Barbara Robbertse

Publication for Hal

Hal citations


Genome mining for peptidases in heat tolerant and mesophilic fungi and putative adaptations for thermostability

BMC Genomics
PMCID: 5819190
PMID: 29463214
DOI: 10.1186/s12864-018-4549-5
call_split See protocol

[…] ungalgenomics.ca/).We inferred a phylogenetic tree to evaluate the evolutionary relationships between the selected species. A super alignment of the selected fungal proteomes was constructed with the Hal pipeline [], allowing for no missing data. Poorly aligned positions and ones with gaps were removed with Gblocks 0.91b []. The following stringent parameters were used: the maximum number of conti […]


Effects of orofacial myofunctional therapy on masticatory function in individuals submitted to orthognathic surgery: a randomized trial

PMCID: 5777416
PMID: 29412368
DOI: 10.1590/1678-7757-2017-0164
call_split See protocol

[…] ce and thus avoid interference and ensure signal quality. The muscles evaluated were: right masseter (RM), left masseter (LM), right temporalis (RT) and left temporalis (LT).Disposable surface double Hal electrodes were used (Miotec Biomedical Equipment, Porto Alegre-RS, Brazil), placed on the skin with conductive paste and fixated using micropore®. The electrodes were placed on the belly of the m […]


Voluntary Ambulation by Upper Limb Triggered HAL® in Patients with Complete Quadri/Paraplegia Due to Chronic Spinal Cord Injury

Front Neurosci
PMCID: 5702458
PMID: 29209163
DOI: 10.3389/fnins.2017.00649
call_split See protocol

[…] The secondary goal of HAL intervention was to regain active knee extension. In patients who were able to flex their hips, a second component was added to each HAL session. In addition to the first component, which involved […]


Internal consistency and item total correlation of patient reported outcome instruments and hemophilia joint health score v2.1 in US adult people with hemophilia: results from the Pain, Functional Impairment, and Quality of life (P FiQ) study

PMCID: 5661843
PMID: 29123383
DOI: 10.2147/PPA.S141391
call_split See protocol

[…] Responses were recorded using a 100-point scale on which higher scores were indicative of better health status. Psycho-metrically based physical and mental health summary scores were also derived.The HAL, was used to assess function across 7 domains (lying/sitting/kneeling/standing, functions of the legs, functions of the arms, use of transportation, self-care, household tasks, and leisure activit […]


Long term impact of joint bleeds in von Willebrand disease: a nested case control study

PMCID: 5685243
PMID: 28572165
DOI: 10.3324/haematol.2017.168617
call_split See protocol

[…] PS>3 of one or more joints as ‘radiological arthropathy’, based on the Limits of Agreement of the PS joint in hemophilia patients.All participants were asked to complete the Hemophilia Activity List (HAL, normalized score: 0–100). This questionnaire has been developed to analyze self-perceived functional abilities in hemophilia., The HAL total and three component sub scores [‘upper extremity activ […]


Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb Girdle Muscular Dystrophy—Preliminary Study

Front Neurosci
PMCID: 5550721
PMID: 28848377
DOI: 10.3389/fnins.2017.00449
call_split See protocol

[…] All patients underwent an 8-week training period of body-weight supported treadmill training (BWSTT) with HAL® exoskeleton. Each patient was scheduled 3 times a week resulting in 24 sessions. The actual time of walking with HAL® was max. 30 min. The exoskeleton was voluntarily triggered by EMG-signals fro […]

Want to access the full list of citations?
Hal institution(s)
National Center for Biotechnology Information, Bethesda, MD, USA; Peace Corps; Oregon State University, Corvallis, OR, USA
Hal funding source(s)
Supported by a National Science Foundation grant (DEB-0732993).

Hal reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review Hal