Provides a maximum probability map in stereotaxic space, which retains quantitative information regarding inter-subject variability. Hammersmith atlas is based on 83 entirely manually delineated regions (“r83”) drawn on Magnetic Resonance Images (MRI) of 30 healthy adult subjects in native space prior to spatial normalisation to MNI space. It can be useful in the monitoring of developmental growth of different brain regions in longitudinal studies and in group comparisons between normal controls and pathological cases of the same age. The atlas can be used as a base to generate individual subject atlases for functional imaging studies.
Imaging Sciences Department, MRC Clinical Sciences Centre and Department of Pediatrics, Imperial College London, Hammersmith Hospital, London, UK; Department of Computing, Imperial College London, South Kensington Campus, London, UK; Division of Neuroscience and MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, UK; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London and National Society for Epilepsy MRI Unit, Chalfont St Peter, UK
Hammersmith atlas funding source(s)
Supported by the UK Engineering and Physical Sciences Research Council and a research scholarship from the “General Arnaoutis” Foundation, by the Medical Research Council, and by the Hammersmith, St Mary's Comprehensive Biomedical Research Centre.