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Haplotype visualization software tools | Population genomics

Haplotype visualization software tools | Population genomics

Haplotype reconstruction is an important tool for understanding the aetiology of human disease. Haplotyping infers the most likely phase of observed genotypes conditional on constraints imposed by the genotypes of other pedigree members. The results of haplotype reconstruction, when visualised appropriately, show which alleles are identical by descent despite the presence of untyped individuals. When used in concert with linkage analysis, haplotyping can help delineate a locus of interest and provide a succinct explanation for the transmission of the trait locus.

Source text:
(Tekman et al., 2017) HaploForge: A Comprehensive Pedigree Drawing and Haplotype Visualisation Web Application. Bioinformatics.

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