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Have yOur Protein Explained HOPE

An easy-to-use web service that analyses the structural effects of a point mutation in a protein sequence. Input your protein sequence and the mutation and HOPE will collect and combine available information from a series of web services and databases and will produce a report, complete with results, figures and animations.

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HOPE classification

  • Animals
    • Homo sapiens

HOPE specifications

Web user interface
Computer skills:
Restrictions to use:

HOPE support


  • Hanka Venselaar <>


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CMBI, NCMLS, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands

Link to literature

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