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hCKSAAP_UbSite specifications


Unique identifier OMICS_05549
Name hCKSAAP_UbSite
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained No


  • Primates
    • Homo sapiens

Publication for hCKSAAP_UbSite

hCKSAAP_UbSite citations


Computational methods for ubiquitination site prediction using physicochemical properties of protein sequences

BMC Bioinformatics
PMCID: 4778322
PMID: 26940649
DOI: 10.1186/s12859-016-0959-z

[…] ediction tool called CKSAAP_UbSite based on the SVM technique and with composition of k-spaced AA pairs as the features []. They also developed a human-specific ubiquitination prediction tools, named hCKSAAP_UbSite, which integrates CKSAAP_UbSite with two other SVM classifiers (i.e., the one based on binary amino acid encoding and the one based on the AAindex [] physicochemical property encoding) […]


Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin proteasome system

Nat Commun
PMCID: 4729826
PMID: 26732515
DOI: 10.1038/ncomms10239

[…] Others) from the same 42-protein set.A large-scale set of experimentally validated Ubsites in human proteins had previously been collected and used to train a human-specific ubiquitin site predictor (hCKSAAP_UbSite). The outcome of ubiquitination was unknown for this set of proteins. This data had been compiled from two recent proteomics-scale assays (in which the Ubsites were assigned based on en […]


Characterization and identification of ubiquitin conjugation sites with E3 ligase recognition specificities

BMC Bioinformatics
PMCID: 4331700
PMID: 25707307
DOI: 10.1186/1471-2105-16-S1-S1

[…] diction performance; 3) the physicochemical properties of residues in the flanking sequences surrounding a Ubi-site are important in the ubiquitination process. For Ubi-site identification in humans, hCKSAAP_UbSite [] has utilized amino acid patterns and properties to improve the prediction performance. The area under the receiver operating characteristic (ROC) curve (AUC) was 0.770 and 0.757 for […]


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hCKSAAP_UbSite institution(s)
State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, China

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