HEX specifications


Unique identifier OMICS_28222
Name HEX
Alternative name Healthy EXomes
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Version 1.0
Maintained Yes


  • person_outline Jose Bras

Publication for Healthy EXomes

HEX citations


Analysis of the prion protein gene in multiple system atrophy

PMCID: 5156473
PMID: 27793473
DOI: 10.1016/j.neurobiolaging.2016.09.021

[…] generation sequencing (). Whole-exome sequencing data were obtained from 462 healthy controls of Caucasian origin older than 65 who were confirmed postmortem to be neuropathologically normal from the Healthy Exomes database. Quality control of exome data included removal of samples with high missingness rate, excess heterozygosity, sex check failure, or evidence of cryptic relatedness. To assess a […]


Inferring Crohn’s disease association from exome sequences by integrating biological knowledge

BMC Med Genomics
PMCID: 4989895
PMID: 27535358
DOI: 10.1186/s12920-016-0189-2

[…] y discriminated by NMTF were clustered in a group by both clustering methods. Since the 8 healthy individuals were easily classified, we excluded them and estimated AUCs for the remaining 42 CD and 6 healthy exomes. As k-means did not provide membership probability, we only compared NMTF and fuzzy clustering for the other healthy individuals and CD patients. When comparing the AUCs, NMTF performed […]

HEX institution(s)
UK Dementia Research Institute, University College London, London, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal; Reta Lila, Weston Research Laboratories, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK; Department of Experimental Neurology, Center for Stroke Research Berlin (CSB), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Germany; Berlin Institute of Health, Berlin, Germany; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA; Human Genetics, School of Molecular Medical Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK; QIMR Berghofer Medical Research Institute, Herston, QLD, Australia; Nuffield Department of Clinical Neurosciences, Oxford Parkinson’s Disease Centre, University of Oxford, UK; Department of Neuroscience, Institute of Psychiatry, King's College London, London, UK; Department of Medical and Molecular Genetics, King’s College London, Guy’s Hospital, London, UK; Molecular Neurology, Research Programs Unit, University of Helsinki, Department of Neurology, Helsinki University Hospital, Helsinki, Finland; Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
HEX funding source(s)
Supported in part by Alzheimer’s Society; the Wellcome Trust/MRC Joint Call in Neurodegeneration award (WT089698); the Intramural Research Programs of the National Institute on Aging, Z01 AG000949-02; an anonymous charitable foundation; Alzheimer's Research UK (ARUK); and the Intramural Research Programs of the National Institute on Aging and the National Institute of Neurological Disease and Stroke, National Institutes of Health (Department of Health and Human Services Project number, ZO1AG000950-10); and, in part, by Penn Alzheimer’s Disease Core Center P30 AG-010124 and Penn Udall Center P50 NS-053488.

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