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An online database for hierarchical groups of orthologs inferred by the Hieranoid algorithm. HieranoiDB with a web interface makes it easy to search and visualize the output of Hieranoid, and to download it in various formats. Searching can be performed using protein description, identifier or sequence. Orthologs are available for the 66 Quest for Orthologs reference proteomes. The ortholog trees are shown graphically and interactively with marked speciation and duplication nodes that show the inferred evolutionary scenario, and allow for correct extraction of predicted orthologs from the Hieranoid trees.

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HieranoiDB classification

HieranoiDB specifications

Restrictions to use:
Community driven:
User data submission:
Database management system:
Data access:
File download, Browse

HieranoiDB support



  • Mateusz Kaduk <>


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Stockholm Bioinformatics Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Solna, Sweden; FH OÖ - University of Applied Sciences Upper Austria, Hagenberg, Austria

Funding source(s)

Vetenskapsradet [2015-05342]; The Swedish Research Council; the Erasmus Mobility Programme

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