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High-throughput screening image analysis software tools | Bright-field microscopy

In recent years, high-throughput microscopy has emerged as a powerful tool to analyze cellular dynamics in an unprecedentedly high resolved manner. The amount of data that is generated, for example in long-term time-lapse microscopy experiments, requires automated methods for processing and analysis. Available software frameworks are well suited for high-throughput processing of fluorescence images, but they often do not perform well on bright field image data that varies considerably between laboratories, setups, and even single experiments.

Source text:
(Buggenthin., 2013) An automatic method for robust and fast cell detection in bright field images from high-throughput microscopy. BMS Bioinformatics.

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