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HiMAP specifications


Unique identifier OMICS_04566
Name HiMAP
Alternative name Human Interactome Map
Restrictions to use None
Maintained Yes


  • Primates
    • Homo sapiens

Publication for Human Interactome Map

HiMAP citations


Comprehensive data resources and analytical tools for pathological association of aminoacyl tRNA synthetases with cancer

PMCID: 4377328
PMID: 25824651
DOI: 10.1093/database/bav022

[…] PPIs based on paralog- and ortholog-based PPI prediction and text mining from STRING, BIND, interologous interaction database (I2D) (), online predicted human interaction database (), human PPI map (HiMAP) () and human PPI prediction (). In addition, the resources that integrate PPIs in individual interactome databases, such as PSICQUIC (EBI) () and NCBI PPI databases, were also used. On the basi […]


IDDI: integrated domain domain interaction and protein interaction analysis system

Proteome Sci
PMCID: 3380739
PMID: 22759586
DOI: 10.1186/1477-5956-10-S1-S9

[…] To construct a new comprehensive DDI database, we merged three 3D structure-based DDI datasets and twenty predicted DDI datasets based on the Pfam identifier. Since the datasets, including P-value, HiMAP, DomainGA and Top-down, use SCOP and InterPro identifier, we converted the SCOP domains to Pfam using SGD http://www.yeastgenome.org and the InterPro domains to Pfam using a mapping table in Int […]


Novel search method for the discovery of functional relationships

PMCID: 3259435
PMID: 22180409
DOI: 10.1093/bioinformatics/btr631

[…] main architectures from Pfam () and InterPro (); metabolic and signaling pathways from HumanCyc (), KEGG (), and Reactome (); protein–protein interactions and protein complexes from CORUM (), DIP (), HiMAP (), HPRD (), IntAct (), MINT (), PDB (; ) and STRING (); disease associations from OMIM (); enzyme classifications from the Enzyme nomenclature database (); gene expression data for different ti […]


Identification of Functional Networks of Estrogen and c Myc Responsive Genes and Their Relationship to Response to Tamoxifen Therapy in Breast Cancer

PLoS One
PMCID: 2496892
PMID: 18714337
DOI: 10.1371/journal.pone.0002987

[…] current in November 2005. Pathway analysis used Onto-Express (http://vortex.cs.wayne.edu/index.htm, ), Ingenuity Pathways Analysis (Ingenuity Systems, Redwood City, CA, http://www.ingenuity.com), and HiMAP (www.himap.org . Gene ontology and functional annotation is presented for only those categories containing ≥3 genes and with an adjusted P value <0.01. […]


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HiMAP institution(s)
Bioinformatics Program, University of Michigan Medical School, Ann Arbor, MI, USA

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