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HitPredict specifications


Unique identifier OMICS_02900
Name HitPredict
Restrictions to use None
Data access File download, Browse
Version 4.0
Maintained Yes
Wikipedia https://en.wikipedia.org/wiki/HitPredict


  • Bacteria
    • Escherichia coli
    • Helicobacter pylori
  • Invertebrates
    • Caenorhabditis elegans
    • Drosophila melanogaster
    • Plasmodium falciparum
  • Plants and Fungi
    • Arabidopsis thaliana
    • Saccharomyces cerevisiae
    • Schizosaccharomyces pombe
  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus
    • Rattus norvegicus

Publications for HitPredict

HitPredict citations


Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs

PMCID: 5574714
PMID: 28851849
DOI: 10.1128/mBio.01276-17

[…] n EF-Tu protein were performed by EMBOSS Needle of Clustal Omega with default parameters, which uses the Needleman-Wunsch alignment algorithm.The protein interactome of E. coli was retrieved from the HitPredict () database, and the network analysis was performed with the network package of Python (). The subnetwork of EF-Tu interaction partners was visualized with Cytoscape (). […]


Bioinformatics analysis of the proteins interacting with LASP 1 and their association with HBV related hepatocellular carcinoma

Sci Rep
PMCID: 5339786
PMID: 28266596
DOI: 10.1038/srep44017

[…] To investigate the proteins that interact with LASP-1, the information of target human proteins was retrieved from different public databases, including IntAct, BioGRID, APID, PINA2.0, Mentha, HitPredict, WiKi-Pi, PIPs, PPI-finder and PrePPI or from the studies reported in PubMed. A total of 390 predicted or experimentally validated LASP-1 interacting proteins were obtained. Given that pred […]


Multidisciplinary investigation links backward speech trait and working memory through genetic mutation

Sci Rep
PMCID: 4738289
PMID: 26838027
DOI: 10.1038/srep20369

[…] 001193601; ZBED5: NP_067034 and NP_001137139), with those made for the correspondent sequences carrying the amino acid change.A list of proteins interacting with Ubiquitin C (UBC) was downloaded from HitPredict (http://hintdb.hgc.jp/htp/), a database of high-confidence protein-protein interactions. Among 8139 interactions, 5961 were predicted with a high-confidence score. We divided the family mem […]


Protein Protein Interaction Detection: Methods and Analysis

Int J Proteomics
PMCID: 3947875
PMID: 24693427
DOI: 10.1155/2014/147648

[…] o the databases. Interaction data is extracted from other databases including BIND and MIPS (Munich Information Center for protein se quences) [], as well as directly from large-scale experiments []. HitPredict is a resource of high confidence protein-protein interactions from which we can get the total number of interactions in a species for a protein and can view all the interactions with confid […]


Innate Immunity Interactome Dynamics

PMCID: 3885269
PMID: 24453478
DOI: 10.4137/GRSB.S12850

[…] We prepared a set of unique mouse interactions from publicly available protein interactions. PPIs were collected from the PPIs databases, InnateDB and HitPredict. Network visualization and analysis was done using Cytoscape. Cytoscape plugins used for the network analysis included MCODE, and Network Analyzer. Network edges were weighted by Pearson’s […]


Assessing the utility of gene co expression stability in combination with correlation in the analysis of protein protein interaction networks

BMC Genomics
PMCID: 3333178
PMID: 22369639
DOI: 10.1186/1471-2164-12-S3-S19

[…] High confidence human protein-protein interactions were taken from the HitPredict [] database. Hubs within the entire network were denoted as proteins with 5 or more interactions. This definition of hubs has previously been shown to be robust []. Hubs in each category ba […]


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HitPredict institution(s)
Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Department of Computational Biology, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan
HitPredict funding source(s)
This work was supported by the Grant-in-Aid for Young Scientists by the Japan Society for the Promotion of Science (26830135).

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