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HLA DB specifications

Information


Unique identifier OMICS_22117
Name HLA DB
Alternative name HLA Database
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes

HLA DB citations

 (34)
library_books

Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma

2018
Nat Commun
PMCID: 5951856
PMID: 29760388
DOI: 10.1038/s41467-018-04008-y

[…] ssed neoepitopes that were capable of being bound by the matched patient human leukocyte antigen (HLA typing). HLA typing was done by aligning sequences from HLA regions against sequences in the IMGT/HLA database. […]

library_books

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

2018
Nat Commun
PMCID: 5931558
PMID: 29717136
DOI: 10.1038/s41467-018-03857-x

[…] o paralogous sequence similarity, we also included all known corresponding alleles for the non-classical genes HLA-DRB3, -DRB4, -DRB5, -DRB6, -DRB7, and -DRB9. Sequences were downloaded from the IMGT/HLA database (accessed 28 July 15). In addition, we included a corresponding exon sequence of HLA-DQB2 from the human reference genome (not represented in the IMGT/HLA database), again to prevent thei […]

call_split

Hidden genomic MHC disparity between HLA matched sibling pairs in hematopoietic stem cell transplantation

2018
Sci Rep
PMCID: 5876349
PMID: 29599509
DOI: 10.1038/s41598-018-23682-y
call_split See protocol

[…] dapest, Hungary) was used for allele assignment of 30 genes at six-digit resolution level comprising both classical HLA genes, non-classical HLA genes and pseudogenes in the MHC region using the IMGT/HLA database’s HLA nomenclature release 3.25.0: HLA-F, HLA-V, HLA-G, HLA-H, HLA-K, HLA-A, HLA-J, HLA-L, HLA-E, HLA-C, HLA-B, HLA-DRA, HLA-DRB1-9, HLA-DQA1, HLA-DQB1, HLA-DOB, HLA-DMB, HLA-DMA, HLA-DOA […]

library_books

PIRCHE II Is Related to Graft Failure after Kidney Transplantation

2018
Front Immunol
PMCID: 5844930
PMID: 29556227
DOI: 10.3389/fimmu.2018.00321

[…] che.org.Since the entire amino acid sequence of relevant HLA molecules is required for the PIRCHE-II algorithm, incomplete amino acid sequences of relevant HLA molecules that were present in the IMGT/HLA database were extrapolated using a nearest-neighbor-based approach as described previously to obtain the complete amino acid sequences of the incomplete HLA allele (). In our analyses, leader pept […]

call_split

Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico

2018
J Virol
PMCID: 5752930
PMID: 29093100
DOI: 10.1128/JVI.01128-17
call_split See protocol

[…] trix, Cleveland, OH, USA) and sequenced on a 3730xl genetic analyzer using BigDye 3.1 chemistry (Thermo Fisher). HLA allele assignment was done using uTYPEv6 (Thermo Fisher) by comparison to the IMGT/HLA database (, ). Using this method, a total of 92 HLA-A, 91 HLA-B, and 39 HLA-C allele pairs within the Common and Well-Documented Catalogue () present polymorphism phase ambiguities at the resoluti […]

library_books

Accuracy of Programs for the Determination of Human Leukocyte Antigen Alleles from Next Generation Sequencing Data

2017
Front Immunol
PMCID: 5733459
PMID: 29326702
DOI: 10.3389/fimmu.2017.01815

[…] oject, it certainly is wise to do some interpretation based on prior population data.Some differences in the relative performances of the programs might be due to the various versions of the IPD-IMGT/HLA database they use. However, we did not try to unify the versions since the programs use their own, slightly modified format of the database and because the programs were all released within a shor […]

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HLA DB funding source(s)
Supported by Ministry of Education, Culture, Sports, Science and Technology of Japan.

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