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HLADR specifications


Unique identifier OMICS_16674
Alternative name Human Leukocyte Antigen-Adverse Drug Reaction
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes


  • person_outline Leming Shi

HLADR citations


Complement Opsonized HIV 1 Alters Cross Talk Between Dendritic Cells and Natural Killer (NK) Cells to Inhibit NK Killing and to Upregulate PD 1, CXCR3, and CCR4 on T Cells

Front Immunol
PMCID: 5936988
PMID: 29760706
DOI: 10.3389/fimmu.2018.00899

[…] in RPMI1640 supplemented with EDTA (Fisher Scientific) in order to disrupt any cell aggregates and were subsequently stained with antibodies specific for CD1c, CD25, CD40, CD56, CD69, CD80, CD86, and HLADR and their corresponding isotype controls (BD Biosciences, Stockholm, Sweden). The cells were analyzed with a FACS flow cytometer (BD Immunocytometry Systems, San Jose, CA, USA) and FlowJo softwa […]


Hyperprogressive Disease in Anorectal Melanoma Treated by PD 1 Inhibitors

Front Immunol
PMCID: 5916968
PMID: 29725330
DOI: 10.3389/fimmu.2018.00797

[…] ty of PDL1 compared to HD. Additionally, between the live PBMC samples, the percentage of the immunosuppressive population of granulocytic myeloid-derived suppressor cells (Gr-MDSC), defined as CD33+/HLADR−/CD15+/CD14−, was increased in the HP patient (Figure B).In the lymphoid cell analysis presented in Figure , the HP patient presented a shift in CD4 and CD8 differentiation, with an increased pr […]


Expression of TIM 3 on Plasmacytoid Dendritic Cells as a Predictive Biomarker of Decline in HIV 1 RNA Level during ART

PMCID: 5923448
PMID: 29597250
DOI: 10.3390/v10040154

[…] c analysis of pDC phenotype, we created a muticolor panel composed of PerCP/Cy5.5-CD11c, BV421-BDCA2, APC-TRAIL, PE-CD4, APC-Fire750-TIM3, FITC-Lin1 (all from Biolegend, San Diego, CA, USA), and V500-HLADR, BV605-CD32 (from BD Biosciences, San Jose, CA, USA). The staining was performed in Brilliant Stain Buffer (BD Biosciences) as recommended by the manufacturer. Cells were fixed in 4% paraformald […]


Natural killer cells activity in a metastatic colorectal cancer patient with complete and long lasting response to therapy

PMCID: 5700388
PMID: 29204427
DOI: 10.12998/wjcc.v5.i11.390

[…] R, CD15 and CD14 (BD Bioscience, San Diego, CA, United States). The classical populations are shown (four types indicated as MDSC1, 2, 3, 4): 1, CD14+/CD124+; 2, CD15+/CD124+; 3, CD33+/SSC+, 4, CD14+/HLADR-/low. For circulating NK cells: CD3, CD16, CD56, CD158a, CD158b, CD161 and CD279 (PD-1). Monoclonal antibodies were used together with the appropriate corresponding isotype controls. […]


Single cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells

Nat Commun
PMCID: 5653675
PMID: 29061960
DOI: 10.1038/s41467-017-01015-3

[…] d specific PBMC subsets and subpopulations as reported in Supplementary Fig. , in detail: T cells (CD45+ CD3+), T helper (CD45+ CD3+ CD4+), T cytotoxic (CD45+ CD3+ CD8+), T naive (CD45RA+ CD27+ CD38− HLADR−), T effector (CD45RA+ CD27− CD38− HLADR−), T memory (CD45RA− CD27+ CD38− HLADR−), and activated (CD38+ HLADR+), B cells (CD45+ CD19+), B naive (HLADR+ CD27−), B memory (HLADR+ CD27+), plasma B […]


Enhanced IFN α production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosus

PMCID: 5649081
PMID: 29052537
DOI: 10.1186/s13075-017-1441-7

[…] ixable Viability Kit (BioLegend, San Diego, CA, USA) and then with combinations of the following monoclonal antibodies against human cell-surface antigens for 30 min on ice: anti-CD11c-Alexa700, anti-HLADR-V500, anti-CD19-APC-H7 (all from BD Biosciences), anti-CD14-ECD, anti-CD56-APC, (both from Beckman Coulter, Brea, CA, USA), anti-CD123-FITC, anti-CD3- PerCPCy5.5, anti-CD56-BV421 (all from BioLe […]


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