HMMvar statistics

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Citations per year

Citations chart

Popular tool citations

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Tool usage distribution map

Tool usage distribution map

Associated diseases

Associated diseases

HMMvar specifications


Unique identifier OMICS_02181
Name HMMvar
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


  • Primates
    • Homo sapiens


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  • person_outline Liqing Zhang <>

Publication for HMMvar

HMMvar in publications

PMCID: 5024463
PMID: 27628848
DOI: 10.1186/s13023-016-0505-0

[…] and affecting gene expression []. a number of computational tools that functionally annotate indels are available including sift-indel [], provean [], ddg-in [], cadd [], privar [], pinpor [], hmmvar [], kd4i [], and vest-indel []. although some of these tools are reported to achieve relatively high sensitivity and specificity values [], predicting the effect of protein-coding […]

PMCID: 4520001
PMID: 26223264
DOI: 10.1186/s40246-015-0040-4

[…] a single variant have been intensively studied. however, the joint effects of multiple variants in the same genes have been largely ignored due to their complexity or lack of data. this paper uses hmmvar, a hidden markov model based approach, to investigate the combined effect of multiple variants from the 1000 genomes project. two tumor suppressor genes, tp53 and phosphatase and tensin […]

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HMMvar institution(s)
Department of Computer Science, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA

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