HOMOG statistics

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Citations per year

Number of citations per year for the bioinformatics software tool HOMOG
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Tool usage distribution map

This map represents all the scientific publications referring to HOMOG per scientific context
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Associated diseases

This word cloud represents HOMOG usage per disease context
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Popular tool citations

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Protocols

HOMOG specifications

Information


Unique identifier OMICS_19325
Name HOMOG
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Windows
Programming languages Pascal
Computer skills Advanced
Stability Stable
Maintained Yes

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Additional information


https://github.com/NCBI-Hackathons/Community_Software_Tools_for_NGS/blob/master/Downstream_Analysis_of_Variants.md

Publications for HOMOG

HOMOG citations

 (6)
library_books

Tissue damage drives co localization of NF κB, Smad3, and Nrf2 to direct Rev erb sensitive wound repair in mouse macrophages

2016
eLife
PMCID: 4963201
PMID: 27462873
DOI: 10.7554/eLife.13024.022

[…] cells, as well as mesenchymal stem cells (). To devise an in vitro model of the acute in vivo response to wounding, we prepared a supernatant from homogenized skin (). This tissue homogenate (tissue homog/TH) provides a complex signal derived from components of disrupted cells (damage associated molecular patterns; DAMPs), the skin microbiome (microbial associated molecular patterns; MAMPs), and […]

call_split

KIAA1462, A Coronary Artery Disease Associated Gene, Is a Candidate Gene for Late Onset Alzheimer Disease in APOE Carriers

2013
PLoS One
PMCID: 3861372
PMID: 24349219
DOI: 10.1371/journal.pone.0082194
call_split See protocol

[…] Weinberg Equilibrium and linkage disequilibrium were checked using Haploview . Linkage analysis was conducted on families using two-point heterogeneity LOD scores (HLOD) calculated using FASTLINK and HOMOG . Both recessive and dominant models with disease allele frequencies of 0.01 and 0.001, respectively, were analyzed. This approach is robust for detecting linkage signals when the underlying mod […]

call_split

Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5

2012
BMC Genet
PMCID: 3309961
PMID: 22369142
DOI: 10.1186/1471-2156-13-12
call_split See protocol

[…] nt linkage for early-onset CAD was performed with a recessive (at risk allele freq 0.20, and penetrance 0.001) and dominant (at risk allele freq 0.01, and penetrance 0.001) model using Vitesse [] and Homog []. These tests were conducted to provide independent validation of SNPs showing evidence for association. In the presence of association and linkage, there tends to be a positive correlation be […]

library_books

TDT HET: A new transmission disequilibrium test that incorporates locus heterogeneity into the analysis of family based association data

2012
BMC Bioinformatics
PMCID: 3292499
PMID: 22264315
DOI: 10.1186/1471-2105-13-13

[…] ing in the linked or unlinked group. This statistic is known as the heterogeneity LOD score (HLOD) [].The A-test has been implemented in a suite of programs to test for heterogeneity vs. homogeneity (HOMOG) []. More complex heterogeneity scenarios are also available in this package: HOMOG1 allows for gender specific differences in θ. HOMOG2, HOMOG3, HOMOG4, distinguish two, three and four types of […]

call_split

Follow up examination of linkage and association to chromosome 1q43 in multiple sclerosis

2009
Genes Immun
PMCID: 2765552
PMID: 19626040
DOI: 10.1038/gene.2009.53
call_split See protocol

[…] linkage peak. Multipoint linkage analysis was performed using MERLIN (). Two-point LOD scores were calculated in FASTLINK (, ), with two-point heterogeneity LOD (HLOD) scores being calculated through HOMOG (). Ordered subset analyses (OSA) were performed using the FLOSS software (). SNPs included in both multipoint linkage analysis and FLOSS were chosen using the implementation of Tagger within th […]

library_books

Genetic and functional association of FAM5C with myocardial infarction

2008
BMC Med Genet
PMCID: 2383879
PMID: 18430236
DOI: 10.1186/1471-2350-9-33

[…] hical Overview of Linkage Disequilibrium package [] and displayed using Haploview [].In the initial screen, two-point linkage using a dominant and recessive model was performed using Fastlink [,] and Homog [] and family-based association was tested using the Association in the Presence of Linkage (APL) test []. We analyzed the GENECARD families together regardless of race because these families fo […]


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HOMOG institution(s)
The Rockefeller University, New York, NY, USA

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