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HPMD

An integrated genomics and proteomics strategy (referred to iMASp - identification of Mutated And Secreted proteins) identify 112 putative mutated tryptic peptides (corresponding to 57 proteins) in the collective secretomes derived from a panel of 18 human colorectal cancer (CRC) cell lines. Central to this iMASp was the creation of Human Protein Mutant Database (HPMD), against which experimentally-derived secretome peptide spectra were searched.

HPMD specifications

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Information

Unique identifier	OMICS_06408
Name	HPMD
Alternative name	Human Protein Mutant Database
Restrictions to use	None
Maintained	Yes

Taxon

Primates
- Homo sapiens

Publication for Human Protein Mutant Database

Identifying mutated proteins secreted by colon cancer cell lines using mass spectrometry.

2012 J Proteomics

PMID: 22796352

HPMD institution(s)

Department of Biochemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

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