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HSD specifications


Unique identifier OMICS_03905
Name HSD
Alternative name Helminth Secretome Database
Restrictions to use None
Database management system MySQL
Community driven No
Data access Browse
User data submission Not allowed
Maintained No


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Publication for Helminth Secretome Database

HSD citations


Genome analysis of Excretory/Secretory proteins in Taenia solium reveals their Abundance of Antigenic Regions (AAR)

Sci Rep
PMCID: 4437048
PMID: 25989346
DOI: 10.1038/srep09683

[…] support for these 44 proteins (). To test whether our obtained AAR values are similar to other known secretomes, we selected the secretomes of 12 helminth species which were recently reported in the Helminth Secretome Database (HSD) and their AAR values were calculated. contains the AAR values for the 12 helminth secretomes (4 nematodes, 4 trematodes and 4 cestodes). Interestingly, the obtained […]


Comparative transcriptome profiling approach to glean virulence and immunomodulation related genes of Fasciola hepatica

BMC Genomics
PMCID: 4429430
PMID: 25956885
DOI: 10.1186/s12864-015-1539-8

[…] e tblastx and blastx, respectively (E value < 10−5).To determine pathogen database related liver fluke transcripts, all F. hepatica transcript sequences were searched against protein sequences of the helminth secretome database (HSD; including secretory databases for nematodes; n = 16,460, trematodes; n = 1,409, cestodes; n = 1,123, and a collection for experimentally determined excretory/secretor […]


Deep mRNA Sequencing of the Tritonia diomedea Brain Transcriptome Provides Access to Gene Homologues for Neuronal Excitability, Synaptic Transmission and Peptidergic Signalling

PLoS One
PMCID: 4342343
PMID: 25719197
DOI: 10.1371/journal.pone.0118321

[…] osecretome database from the Tritonia TSA, derived from a dataset of 9,832 completely non-redundant protein sequences (). Our criteria for selection was similar to that recently used for generating a helminth secretome database [], where sequences were filtered based on the presence of an N-terminal signal peptide (SignalP []), the absence of transmembrane helices (tmHMM []), and the absence of mi […]


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HSD institution(s)
Department of Chemistry and Biomolecular Sciences and ARC Centre of Excellence in Bioinformatics, Macquarie University, Sydney, NSW, Australia; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
HSD funding source(s)
Supported by Macquarie University with the grant of Australian Postgraduate Award scholarship and Post Graduate Research Fund.

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