Provides open, user-friendly access to detailed data on the rapidly growing list of HIV broadly neutralizing antibodies (bNAbs), including neutralization profiles, sequences and three-dimensional structures (when available). It also provides an extensive list of visualization and analysis tools, such as heatmaps to analyse neutralization data as well as structure and sequence viewers to correlate bNAbs properties with structural and sequence features of individual antibodies. The goal of the bNAber database is to enable researchers in this field to easily compare and analyse available information on bNAbs thereby supporting efforts to design an effective vaccine for HIV/AIDS.
A database of mutagenesis and mutation information on Human Immunodefiency Virus (HIV). Hivmut describes the phenotypes of 7,608 unique mutations at 2,520 sites in the HIV proteome, resulting from the analysis of 120,899 papers. The mutation information for each protein is organised in a residue-centric manner and each residue is linked to the relevant experimental literature. The importance of HIV as a global health burden advocates extensive effort to maximise the efficiency of HIV research. The HIV mutation browser provides a valuable new resource for the research community.
Deals with HIV protein sequence, sequence conservation, and functional sites. HIVToolbox consists of a database of resources extracted from various datasets from the Protein Data Bank, NCBI, or Los Alamos HIV sequence database. It allows users to perform interactive visual mining tasks for comparing structures with the aim of assisting with experimental design, hypothesis producing and interpretation of experiments.