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hybridlab specifications


Unique identifier OMICS_20128
Name hybridlab
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages Java
Computer skills Advanced
Stability No
Java Runtime Environment
Maintained No


No version available


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Publication for hybridlab

hybridlab citations


Hybridization and differential introgression associated with environmental shifts in a mistletoe species complex

Sci Rep
PMCID: 5882953
PMID: 29615778
DOI: 10.1038/s41598-018-23707-6
call_split See protocol

[…] parental individuals obtained from previous STRUCTURE included in the analysis.To define assignment thresholds to each hybrid category used for our results, we performed hybridization simulations in HYBRIDLAB. For this, we used the individuals classified as parental in the STRUCTURE analysis as the starting populations and simulated 50 hybrids for several generations: first, second and third gene […]


Low rates of hybridization between European wildcats and domestic cats in a human‐dominated landscape

Ecol Evol
PMCID: 5817136
PMID: 29468044
DOI: 10.1002/ece3.3650
call_split See protocol

[…] In order to investigate the power of our markers to detect wildcat and domestic cat hybrid classes, we generated hybrid genotypes using Hybridlab (Nielsen, Bach, & Kotlicki, ). For this purpose, we selected complete empirical microsatellite genotypes (no missing loci) from the roadkill dataset that assigned to either parental subspeci […]


Introgressive replacement of natives by invading Arion pest slugs

Sci Rep
PMCID: 5668256
PMID: 29097725
DOI: 10.1038/s41598-017-14619-y
call_split See protocol

[…] entify the optimal threshold q-value (i.e. the probability of belonging to a genetic cluster) for distinguishing between non-admixed individuals and potential hybrids between the two species, we used Hybridlab 1.0 to simulate parental and hybrid genotypes in each transect. The parental genotypes used for the simulations consisted of 50 individuals assigned to their genetic cluster with a q-value a […]


Identification of Genetically Important Individuals of the Rediscovered Floreana Galápagos Giant Tortoise (Chelonoidis elephantopus) Provides Founders for Species Restoration Program

Sci Rep
PMCID: 5597637
PMID: 28904401
DOI: 10.1038/s41598-017-11516-2
call_split See protocol

[…] ment tests were undertaken using three additional methods. Prior to implementing these methods, we expanded the reference database to include simulated genotypes. These genotypes were simulated using HYBRIDLAB version 1.0, and corresponded to individuals arising from crosses within and among the genetically distinct C. becki populations on Volcano Wolf (PBL and PBR), and the two saddle-backed spec […]


Hybridization patterns in two contact zones of grass snakes reveal a new Central European snake species

Sci Rep
PMCID: 5547120
PMID: 28785033
DOI: 10.1038/s41598-017-07847-9
call_split See protocol

[…] ulted in two clusters, one corresponding to helvetica (blue lineage) and the other to all other lineages.To explore which individuals represent helvetica hybrids, hybrid genotypes were modelled using hybridlab 1.0. For doing so, 20 non-admixed representatives of each lineage occurring in the Rhine contact zone were selected (blue and yellow lineages) as pure parental genotypes. Using these data, 2 […]


Development of a Traceability System Based on a SNP Array for Large Scale Production of High Value White Spruce (Picea glauca)

Front Plant Sci
PMCID: 5524734
PMID: 28791035
DOI: 10.3389/fpls.2017.01264

[…] the 73 elite parents, and following the mating scheme involving the 68 controlled crosses conducted between these parents in the elite breeding program. The script was adapted from the commonly used Hybridlab software (Nielsen et al., ), in which, for any given cross, an allele from each parent and for each marker is randomly selected to generate the offspring genotype following Mendelian expecta […]


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hybridlab institution(s)
Department of Inland Fisheries, Danish Institute for Fisheries Research, Silkeborg, Denmark; Department of Theoretical Ecology, Lund University, Lund, Sweden; Department of Computer Science, University of Aarhus, Aarhus, Denmark

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