Hydra-Multi specifications


Unique identifier OMICS_07988
Name Hydra-Multi
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages C++
Computer skills Advanced
Stability Stable
SAMtools, PySam, set ulimit
Maintained Yes


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  • person_outline Aaron R. Quinlan <>

Publication for Hydra-Multi

Hydra-Multi in publications

PMCID: 5476599
PMID: 28630418
DOI: 10.1038/s41598-017-02212-2

[…] the broad spectral range, commercial silicon wafer was used in order to avoid the glass high background., ters measurements were performed using a commercial scanning probe microscope (spm) system hydra multi view 4000 from nanonics imaging in the upright microscope configuration. the light path was free-space coupled to a labram hr micro-raman spectrometer from horiba jobin yevon. the raman […]

PMCID: 4666360
PMID: 26503250
DOI: 10.1093/nar/gkv1089

[…] assembly approaches have received increasing application to next-generation sequencing data for breakpoint identification. tools such as tigra (), a modification of the sga assembler used in hydra-multi (,), and the use of a de brujin graph-based approach in svmerge () have been developed to assemble structural variant breakpoints from population scale or heterogeneous tumour sequencing […]

PMCID: 5424792
PMID: 28516020
DOI: 10.4161/idp.25954

[…] and matched normal samples, in the form of blood or normal solid tissue, were subjected to the illumina paired-end sequencing by tcga., to identify structural variant (sv) breakpoints, they used hydra-multi, a new multisample version of their hydra paired-end mapping algorithm using population-based clustering. read pairs from all 64 tumor samples and 65 normal samples were combined […]

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Hydra-Multi institution(s)
Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA
Hydra-Multi funding source(s)
This work was supported by an NIH/NHGRI [1R01HG006693-01 to A.R.Q.] and an NIH New Innovator Award [DP2OD006493-01] and a Burroughs Wellcome Fund Career Award [to I.M.H.].

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