Gives access to many free software tools for sequence analysis. EMBOSS aims to serve the molecular biology community. It permits the creation and the release of software in an open source spirit. This tool is useful for sequence analysis into a seamless whole. It is free of charge and is available in open source.
Provides access to a variety of public and in-house bioinformatics tools. The MPI Bioinformatics Toolkit integrates a selected set of most useful methods for the analysis of protein sequences and structures. It offers more of 50 interconnected tools, so that the results of one tool can be forwarded to other tools. It also includes a useful platform for teaching bioinformatic enquiry to students in the life sciences.
Allows protein sequence analysis. ANTHEPROT is able to interactively couple multiple alignments with secondary structure predictions. It can submit tasks on a remote server and retrieve data from a remote Web server. This tool is a complete solution for Intranet protein sequence analysis for universities, biological research institutes or biomedical companies. It permits users to integrate secondary structure predictions within multiple alignment and full interactive editing of alignments.
Explores the interactions of helical peptides of up to 50 residues with membranes of various types. MCPep is a server designed for non-experts wishing to perform Monte Carlo (MC) simulations of helical peptides in association with lipid membranes. The software simulates the peptide in the aqueous phase and membrane environments, both described implicitly. It reports the main determinants of peptide-membrane interactions, e.g. average location and orientation in the membrane, free energy of membrane association and the peptide's helical content.
Provides a useful screening operation for identifying their membrane-based segments. TM Finder is an application that automates and implements the concept of dual threshold hydrophobicity and nonpolar phase helicity requirements to locate protein transmembrane (TM) segments from primary sequences alone. This program also has the power to distinguish essentially unequivocally between membrane and nonmembrane proteins.
Performs calculation of the basic property of peptides/proteins, including the isoelectric point (pI), hydrophobicity (Hy) and mass weight (MW). ProPAS allows analysis of the data in local computer, which can be used to process small or large-scale datasets. The software provides the statistic results to get the protein/peptide number distribution of these physicochemical properties.
Allows computation of properties of protein sequences. PHYSICO is an automated standalone, multipurpose procedure for analysis of protein sequences. The software acts as position-based-substitution (PWS) analyzer as 3-in-1 form. It provides users flexibility for input-parameters and helps auto-preparation of BLOCKFASTA file.