i-rDNA specifications


Unique identifier OMICS_10280
Name i-rDNA
Interface Web user interface
Restrictions to use None
Input data Metagenomic sequence data sets (fasta format)
Computer skills Basic
Stability No
Maintained No


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Publication for i-rDNA

i-rDNA in publications

PMCID: 5698767
PMID: 28906055
DOI: 10.1111/mmi.13838

[…] telomeric location of vsg within the bloodstream form es is not essential for adequate levels of expression., we next expressed ectopic vsg117 from other genomic locations, including a tagged pol i rdna spacer, a pol ii‐transcribed α‐β tubulin locus, or upstream of a silent pol i procyclin transcription unit (fig. a), where constructs integrating in the rdna spacer or upstream […]

PMCID: 5300755
PMID: 28182764
DOI: 10.1371/journal.pone.0171870

[…] comparative analyses were conducted using a bayesian phylogenetic tree that included 55 species of uca [], inferred from nucleotide sequences of mitochondrial 16s and cytochrome c oxidase subunit i rdna, and nuclear 28s rdna genes. this is the only phylogeny available with actual branch lengths in terms of genetic divergence. the tree was pruned to match the 24 species […]

PMCID: 4376722
PMID: 25815716
DOI: 10.1371/journal.pgen.1005113

[…] and ccr4δ cells grown to log phase in ypd. surprisingly, under these conditions we detected significantly elevated levels of pol i throughout the rdna suggesting ccr4-not normally acts to limit pol i rdna binding (). deficiencies in pol i regulators can also influence rdna copy number so we next determined whether ccr4δ resulted in significant changes to rdna copy number. utilizing our chip […]

PMCID: 3586713
PMID: 23443558
DOI: 10.1038/ncomms2539

[…] n-terminal tails of h3 and h4 in vitro in a nad+-dependent manner, it is associated with the telomeric clusters and also highly enriched in the nucleolus, the nuclear compartment dedicated to pol i rdna transcription. however, so far no nucleolar function had been assigned to pfsir2a., the sir2 family of deacetylases has a wide range of cellular targets, including the rdna locus, […]

PMCID: 3413144
PMID: 22553361
DOI: 10.1093/nar/gks345

[…] steady-state rrna levels. this result is not surprising given that we did not detect significant changes in rrna expression in the uaf30δ mutant which is known to significantly decrease rna pol i rdna binding (). yeast cells can adjust their rates of rrna synthesis such that cells containing only 42 rdna repeats express equivalent levels of rrna as control cells carrying a normal repeat […]

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i-rDNA institution(s)
Bio-Sciences R&D Division, TCS Innovation Labs, Tata Research Development & Design Centre, Tata Consultancy Services Ltd, Maharashtra, India

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