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iBBiG specifications


Unique identifier OMICS_01802
Name iBBiG
Alternative name Iterative Binary Biclustering of Genesets
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License Artistic License version 2.0
Computer skills Advanced
Version 1.24.0
Stability Stable
methods, stats4, xtable, biclust, ade4
Maintained Yes


No version available


Publication for Iterative Binary Biclustering of Genesets

iBBiG citations


Targeted Sequencing and Meta Analysis of Preterm Birth

PMCID: 4862658
PMID: 27163930
DOI: 10.1371/journal.pone.0155021

[…] for each of the 48 patients. the significant gene sets from the gsea of each patient were then compared by adapting a newly described meta-analytic approach known as iterative binary bi-clustering (ibbig) []. the ibbig algorithm identifies “modules” of gene sets and patient subsets from binary data []. our analytical pipeline is illustrated in ., for each module we analyzed the patient subsets […]


Composition and temporal stability of the gut microbiota in older persons

PMCID: 4681863
PMID: 26090993
DOI: 10.1038/ismej.2015.88

[…] subjects. to refine our understanding of diet–microbiota associations and differential taxon abundance, we adapted an iterative bi-clustering algorithm (iterative binary bclustering of gene sets (ibbig)) and applied it to microbiota composition data from 732 faecal samples from 371 eldermet cohort subjects, including longitudinal samples. we thus identified distinctive microbiota […]

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iBBiG institution(s)
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA

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