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ICGC specifications

Information


Unique identifier OMICS_05526
Name ICGC
Alternative name International Cancer Genome Consortium
Restrictions to use None
Maintained Yes
Wikipedia https://en.wikipedia.org/wiki/International_Cancer_Genome_Consortium

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Núria López-Bigas

Publications for International Cancer Genome Consortium

ICGC citations

 (70)
library_books

Cancer driver mutation prediction through Bayesian integration of multi omic data

2018
PLoS One
PMCID: 5940219
PMID: 29738578
DOI: 10.1371/journal.pone.0196939

[…] Large-scale cancer genome projects, such as The Cancer Genome Altas (TCGA), and the International Cancer genome Consortium (ICGC) have systematically catalogued hundreds of thousands of somatic mutations in a wide variety of adult and pediatric cancers. However, the functional signif […]

library_books

Highly similar genomic landscapes in monoclonal B cell lymphocytosis and ultra stable chronic lymphocytic leukemia with low frequency of driver mutations

2018
Haematologica
PMCID: 5927998
PMID: 29449433
DOI: 10.3324/haematol.2017.177212

[…] ound in the PMN samples.To assess whether the non-synonymous mutations identified here might be potentially relevant to CLL, we compared our findings to the variants reported by Puente et al. and the International Cancer Genome Consortium (ICGC) database. Overall, the vast majority of genes carrying mutations in our series were also reported as mutated in either or both datasets: 94% in LC-MBL, 89 […]

library_books

NIPS, a 3D network integrated predictor of deleterious protein SAPs, and its application in cancer prognosis

2018
Sci Rep
PMCID: 5902451
PMID: 29662108
DOI: 10.1038/s41598-018-24286-2

[…] high-throughput sequencing technologies have promoted the identification of many somatic mutations by ongoing initiatives, such as The Cancer Genome Atlas (TCGA; http://cancergenome.nih.gov) and the International Cancer Genome Consortium (ICGC; https://dcc.icgc.org),. These initiatives have shown that cancer genomes often contain hundreds or thousands of mutations; however, not all of these mutat […]

library_books

SRARP and HSPB7 are epigenetically regulated gene pairs that function as tumor suppressors and predict clinical outcome in malignancies

2018
Mol Oncol
PMCID: 5928383
PMID: 29577611
DOI: 10.1002/1878-0261.12195

[…] Broad Institute Genome Sequencing Center using the MuTect method (Cibulskis et al., ). MuTect calls from TCGA cohorts were combined to produce the mutation dataset.Moreover, Pan‐Cancer datasets from International Cancer Genome Consortium (ICGC) were accessed using the UCSC Xena browser and ICGC Data Portal (https://dcc.icgc.org/). ICGC datasets were applied to further assess the association of SR […]

library_books

Dissecting super enhancer hierarchy based on chromatin interactions

2018
Nat Commun
PMCID: 5838163
PMID: 29507293
DOI: 10.1038/s41467-018-03279-9

[…] re downloaded from the UCSC Genome Browser. The sitepro plots of conservation score were plotted within ±200 bp centered by CTCF motif sites.Known somatic mutation loci in cancer were downloaded from International Cancer Genome Consortium (ICGC) Data Portal (release 23). The sitepro plots of mutation frequencies were plotted within ±200 bp centered by CTCF motif sites with a 10 bp smoothing window […]

library_books

Pan cancer screen for mutations in non coding elements with conservation and cancer specificity reveals correlations with expression and survival

2018
PMCID: 5765157
PMID: 29354286
DOI: 10.1038/s41525-017-0040-5

[…] tential of individual cases can be supported by a correlation of presence of mutations with gene expression or patient survival.Concerted sequencing efforts and systematic statistical analysis by the International Cancer Genome Consortium (ICGC) and others have successfully cataloged protein-coding driver genes and their mutational frequency in pan-cancer and individual cancer types., While this i […]

Citations

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ICGC institution(s)
Research Unit on Biomedical Informatics, University Pompeu Fabra, Barcelona, Spain

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