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iDBPs specifications


Unique identifier OMICS_03575
Name iDBPs
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for iDBPs

iDBPs citations


iDNAProt ES: Identification of DNA binding Proteins Using Evolutionary and Structural Features

Sci Rep
PMCID: 5668250
PMID: 29097781
DOI: 10.1038/s41598-017-14945-1

[…] nter) was proposed to identify DNA-binding proteins using structure comparison and evaluation of a statistical potential derived from the interactions between DNA base pairs and protein residues. The iDBPs server was proposed in used global features like average surface electrostatic potential, the dipole moment and cluster-based amino acid conservation patterns. Low resolution α-carbon only model […]


Vitamin D and Hypertension

PMCID: 5641496
PMID: 29042901
DOI: 10.5049/EBP.2017.15.1.1

[…] for specific tissues and cell types to utilize. DBP linked vitamin D is actively transported by megalin mediated endocytosis in the various target cells, and intracellular vitamin D binding proteins (IDBPs) help to regulate the intracellular metabolism of vitamin D thereafter.The renal production of 1,25 (OH)2D is tightly regulated by 1, 25-dihydroxyvitamin D itself, plasma PTH levels as a signal […]


Potential DNA binding and nuclease functions of ComEC domains characterized in silico

PMCID: 5031224
PMID: 27318187
DOI: 10.1002/prot.25088

[…] PSI‐BLAST with an E‐value of 0.0001. The models, along with comparator crystal structures of known function were submitted to the structure‐based nucleic acid binding prediction servers DNABIND, and iDBPs. […]


Expanding the catalog of cas genes with metagenomes

Nucleic Acids Res
PMCID: 3936711
PMID: 24319142
DOI: 10.1093/nar/gkt1262

[…] e a conserved motif that is phenylalanine and tyrosine rich (Supplementary Figure S8A), and are likely to form helical structures [as predicted by I-TASSER ()] and bind DNA molecules [as predicted by iDBPs server ()] (see Supplementary Figure S8B for a model of the complex structure).The last example Cash6, is found associated with the CRISPR–Cas subtype IC-variant, and shares similar genomic cont […]


A Sleeping Beauty DNA transposon based genetic sensor for functional screening of vitamin D3 analogues

BMC Biotechnol
PMCID: 3083354
PMID: 21473770
DOI: 10.1186/1472-6750-11-33

[…] in D binding protein (DBP). Transport across the cellular membrane is mediated by diffusion or megalin-mediated endocytosis prior to binding of the ligand by intracellular vitamin D binding proteins (IDBPs) within the cytoplasm. Upon ligand binding, VDR undergoes a conformational change that allows interaction with other cellular proteins. The VDR-ligand complex is transported across the nuclear m […]


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iDBPs institution(s)
Department of Biochemistry, The George S Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Israel

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