Analyzes methylation intensity data generated from tiling arrays to locate DMRs across a large set of samples simultaneously. ICDMR provides a way to calculate the concordance between adjacent probes, where concordance measures the consistency of methylation status between two probes among individuals. A population-based distribution is also used to assess the significance of the concordance.

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Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Department of Mathematics, National Changhua University of Education, Changhua, Taiwan

Funding source(s)

This research was supported by National Science Council grants (NSC101-2811-B-001-041, NSC100-2811-B-001-071) of Taiwan.

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