Unlock your biological data
Two haplotypes are identical by descent if they share the same alleles inherited from a common ancestor. Identity by descent (IBD) can be considered on various timescales. Emerging applications for the detected IBD segments include IBD mapping, haplotype phase inference, genotype imputation, and inference of population structure. Most IBD detection methods are based on hidden Markov models (HMMs) in which, at each DNA locus, a hidden state indicates presence or absence of IBD.