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IGGalaxy specifications


Unique identifier OMICS_07009
Name IGGalaxy
Alternative name ImmunoGlobulin Galaxy
Interface Web user interface
Restrictions to use None
Biological technology Illumina, Roche
Programming languages Perl, Python, R
Computer skills Basic
Stability Stable
Maintained No

Publication for ImmunoGlobulin Galaxy

IGGalaxy citations


Human IgG2 and IgG4 expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age

Immunol Cell Biol
PMCID: 5636940
PMID: 28546550
DOI: 10.1038/icb.2017.43

[…] ltiplex identifier sequence and trimmed using the Antigen Receptor Galaxy (ARGalaxy) tool. Fasta files were uploaded in IMGT/High V-Quest, and subsequently, the IMGT output files were analyzed in the IGGalaxy tool. To exclude low-quality reads, we only included transcripts of which the exact CDR1-CDR3 nucleotide sequence occurred twice or more. Information on junction characteristics, CDR3 length, […]


Vidjil: A Web Platform for Analysis of High Throughput Repertoire Sequencing

PLoS One
PMCID: 5106020
PMID: 27835690
DOI: 10.1371/journal.pone.0166126

[…] studies, allowing to easily navigate between statistical informations on the clonotypes and detailed view of some sequences and enabling user annotations. Some software try to fill this gap, such as IgGalaxy. However it relies on software that are not specifically suited to the analysis of high-throughput sequencing (with millions of sequencing reads). Also the user needs to upload the results fr […]


Evaluation of the Antigen Experienced B Cell Receptor Repertoire in Healthy Children and Adults

Front Immunol
PMCID: 5066086
PMID: 27799928
DOI: 10.3389/fimmu.2016.00410

[…] erienced repertoire of 38 HD from cord blood to the age of 74 years. We used next generation sequencing to generate this reference data set and analyzed the repertoire using an updated version of our IGGalaxy analysis pipeline (). […]


Strategies for B Cell Receptor Repertoire Analysis in Primary Immunodeficiencies: From Severe Combined Immunodeficiency to Common Variable Immunodeficiency

Front Immunol
PMCID: 4389565
PMID: 25904919
DOI: 10.3389/fimmu.2015.00157

[…] R products were sequenced on the 454 GS junior instrument according the manufacturer’s recommendations. Sequences were demultiplexed based on their multiplex identifier sequence and trimmed using the IGGalaxy tool (). Fasta files were uploaded in IMGT/High-V-Quest (), and subsequently, the IMGT output files were analyzed in the IGGalaxy tool (). Information on junction characteristics, CDR3 length […]

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IGGalaxy institution(s)
Department of Bioinformatics, Erasmus University Medical Center, Rotterdam, Netherlands

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