IgRepertoireConstructor

Performs error-correction of immunosequencing reads and uses mass spectra to validate the constructed antibody repertoires. IgRepertoireConstructor takes Illumina MiSeq paired end reads as an input and expect that each left and right reads overlap and cover variable region of antibody. IgRepertoireConstructor stitches paired-end reads and removes contaminations using alignment of stitched reads against Ig germline database. This procedure significantly improves quality of input reads and allows one to constructs reads covering variable region of antibody.