bookmark XMSF / Microscopy Mean-Shift Filtering New Denoises and pre-segments noisy electron microscopy tomograms. XMSF is a program that filters noise while preserving the structures of interest. The software can be used to process both 2D (images) and 3D (volumes) datasets. It has potential of application in electron tomography (ET). This program is available both as a stand-alone statically compiled executable and as part of the Xmipp image processing software package.