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Image registration is used for aligning two images of the same object into a common coordinate system presenting the fused image. The one image is usually referred as reference and the other as sensed (or referred). Image registration is a spatial transform. The images can be acquired from different angles, at different times, by different or same modalities. A typical example of the use of image registration from different modalities in nuclear medicine is the combination of SPECT and CT images (SPECT/CT) or PET and CT (PET/CT).
(Lyra., 2011) MATLAB as a Tool in Nuclear Medicine Image Processing. Nat Methods. Computer and Information Science