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Image segmentation is one of the most important tasks in medical image analysis and is often the first and the most critical step in many clinical applications. In brain MRI analysis, image segmentation is commonly used for measuring and visualizing the brain’s anatomical structures, for analyzing brain changes, for delineating pathological regions, and for surgical planning and image-guided interventions.
(Despotovic., 2015) MRI Segmentation of the Human Brain: Challenges, Methods, and Applications. Computational and Mathematical Methods in Medicine.