Image spectra analysis software tools | Mass spectrometry imaging
Mass spectrometry imaging (MSI) was developing fast with the invention of various in-situ ionization sources and their combinations with different mass analyzers for specific analytical demands. The greatest power of MSI lies in its ability to simultaneously acquire the molecule features and their morphological distributions in one single MSI experiment. Nowadays, it has become the most promising analytical tool in the field of life science, metabolomics, proteomics, drug development, clinical diagnosis and molecular mechanism research.
A vendor-neutral interface built on the Matlab platform designed to view and perform data analysis of Mass Spectrometry Imaging (MSI) data. A standalone version of MSiReader for which Matlab is not required is also provided. People who are unfamiliar with the Matlab language will have little difficulty navigating the user friendly interface, and users with Matlab programming experience can adapt and customize MSiReader for their own needs.
Enables construction, manipulation, analysis and comparison of mass spectrometry (MS) images. MSight is designed for 2-D representation, as well as visual analysis and comparison of datasets obtained from protein or peptide separation combined to MS. The software allows navigation through large volumes of data and provides visualization tools to discriminate peptide or protein from noise or to perform differential analysis. It aims to improve understanding of correlated high-throughput MS.
Presents an improved data analysis pipeline based on a new peak picking method for exploring imaging mass spectrometry data. EXIMS consists of five consecutive main steps: where the first step involves spectra preprocessing. Then, Sliding Window Normalization (SWN) is used to normalize the spectra and limit the influence of high intensity peaks. Third, image de-noising and contrast enhancement are used to improve the visualization of intensity images. Fourth, peak picking is performed by processing the individual intensity images. Finally, intensity images are clustered using the fuzzy cmeans clustering algorithm.
Revolutionizes the analysis of Mass Spectrometry Imaging data with a limitless software which helps to visualize, normalize, validate and interpret large MSI data. Multimaging integrates the latest statistical tools for a better biomarker discovery. It visualizes 50 different datasets (>1Terabytes) at a same time with the same intensity scale for a robust data interpretation and quantifies biomarkers and xenobiotics (drug and metabolites) to get accurate information.
A comprehensive bioinformatics tool for MALDI tissue imaging, facilitates data processing, visualization and analysis of spatial distribution of individual ions across the sampled locations on a tissue section. The program accepts imaging mass spectrometric data in standard file formats. MALDIVision generates an ion intensity map for any m/z in the analysis range, enabling simultaneous imaging of many compounds. Users can view images in 2-D and in 3-D.
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