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Mass spectrometry imaging (MSI) was developing fast with the invention of various in-situ ionization sources and their combinations with different mass analyzers for specific analytical demands. The greatest power of MSI lies in its ability to simultaneously acquire the molecule features and their morphological distributions in one single MSI experiment. Nowadays, it has become the most promising analytical tool in the field of life science, metabolomics, proteomics, drug development, clinical diagnosis and molecular mechanism research.
(He., 2018) MassImager: A software for interactive and in-depth analysis of mass spectrometry imaging data. Analytica Chimica Acta.