iMETHYL specifications


Unique identifier OMICS_28697
Restrictions to use None
Community driven No
Data access File download, Browse
User data submission Not allowed
Maintained Yes


  • person_outline Atsushi Shimizu

Publication for iMETHYL

iMETHYL citations


Genome wide meta analysis in Japanese populations identifies novel variants at the TMC6–TMC8 and SIX3–SIX2 loci associated with HbA1c

Sci Rep
PMCID: 5701039
PMID: 29170429
DOI: 10.1038/s41598-017-16493-0

[…] Whole-genome and transcriptome data from 105 Japanese subjects registered in a multi-omics database (iMETHYL) were analysed to search for significant cis-eQTL variant-gene pairs. Pairs of a novel lead variant and neighbouring genes within ±100 kb were tested. Adaptor trimming, mapping, quality contro […]


Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling

Nat Commun
PMCID: 4396391
PMID: 25849564
DOI: 10.1038/ncomms7758

[…] C4 (). The two stable isotope-labelled methionines are nearly isobaric but differ in the distribution of the additional mass; we, therefore, termed this labelling strategy isomethionine methyl-SILAC (iMethyl-SILAC). The methyl groups transferred during protein methylation are still either light or heavy, but methionines incorporated during protein synthesis are nearly isobaric. As a result, methyl […]

iMETHYL institution(s)
Division of Biomedical Information Analysis, Iwate Medical University, Morioka, Japan; Division of Biobank and Data Management, Iwate Medical University, Morioka, Japan; Laboratory of Bioinformatics, Department of Molecular Microbiology, Faculty of Life Sciences, Tokyo University of Agriculture, Setagaya, Tokyo, Japan; Department of Anatomy, School of Medicine, Institute for Biomedical Sciences, Iwate Medical University, Morioka, Japan; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Morioka, Japan; Iwate Medical University, Morioka, Japan; Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Morioka Japan
iMETHYL funding source(s)
Supported by the Tohoku Medical Megabank Project (Special Account for Reconstruction from the Great East Japan Earthquake) from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) and the Japan Agency for Medical Research and Development (AMED).

iMETHYL reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review iMETHYL