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IMEX specifications


Unique identifier OMICS_09604
Alternative name IMmunEXplorer
Software type Framework/Library
Interface Command line interface, Graphical user interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages C#
Computer skills Advanced
Version 1.0
Stability Beta
Net framework
Maintained Yes


No version available


  • person_outline Susanne Schaller

Publication for IMmunEXplorer

IMEX citations


Cholangiocarcinoma associated genes identified by integrative analysis of gene expression data

PMCID: 5866017
PMID: 29436659
DOI: 10.3892/mmr.2018.8594

[…] Network analyst uses a comprehensive, high-quality PPI database downloaded from InnateDB (), which is part of the International Molecular Exchange (IMEx) consortium (). It additionally contains manually curated protein interaction data from published literature and experimental data from a number of PPI databases, including IntAct (), MINT (), DI […]


Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data

Nucleic Acids Res
PMCID: 5753374
PMID: 29155944
DOI: 10.1093/nar/gkx1116

[…] scale screen data in addition to manually curated data from small studies, and thus provide much larger networks. Several resources integrate interactions from multiple public resources. For example, IMEx (), a consortium effort, integrates the binary protein–protein interaction (PPI) data from multiple resources such as DIP and IntAct. Another example is iRefWeb (), which integrates both physical […]


Surface PD L1, E cadherin, CD24, and VEGFR2 as markers of epithelial cancer stem cells associated with rapid tumorigenesis

Sci Rep
PMCID: 5575243
PMID: 28851898
DOI: 10.1038/s41598-017-08796-z

[…] jected to SDS-PAGE and Western immunoblotting. The prey protein bands were normalized using RalBP1 (bait) using ImageJ software–based densitometry. Protein interaction data have been submitted to the IMEx ( consortium through IntAct and assigned the identifier IM‐24526. […]


Equine skeletal muscle adaptations to exercise and training: evidence of differential regulation of autophagosomal and mitochondrial components

BMC Genomics
PMCID: 5551008
PMID: 28793853
DOI: 10.1186/s12864-017-4007-9

[…] ssion levels were found to be significantly correlated in the respective cohort (i.e. UR, UE or TR). Experimentally validated protein-protein interactions (PPIs) for human, that were annotated to the IMEx (International Molecular Exchange consortium) standard [], were then obtained (12–09-2016) from the IntAct database [] using the PSICQUIC web-service [] (see Additional file for the specific que […]


Exploring the cross talk between ER stress and inflammation in age related macular degeneration

PLoS One
PMCID: 5524348
PMID: 28742151
DOI: 10.1371/journal.pone.0181667

[…] d in International Molecular Exchange (IMEx) consortium members comprising I2D, InnateDB, IntAct, MBInfo, MINT, HPIDB, UCL-BHF, UniProt and MolCon through the PSI Common Query Interface (PSICQUIC)[]. IMEx-curated databases commit to apply common curation strategies to provide a nonredundant protein-interaction framework ([]. Different types of interaction data which […]


3D: diversity, dynamics, differential testing – a proposed pipeline for analysis of next generation sequencing T cell repertoire data

BMC Bioinformatics
PMCID: 5327583
PMID: 28241742
DOI: 10.1186/s12859-017-1544-9

[…] exible toolkit for the processing and analysis of antigen receptor repertoire sequencing data at single-cell level by a relational database. Some of the tools, such as repgenHMM [], IMonitor [], IMEX/IMmunEXplorer [], Change-O [], ImmunediveRsity [], and VDJtools [] etc., could also measure repertoire diversity, but they only rely on one or two diversity indices, such as Shannon or Gini diversity. […]


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IMEX institution(s)
University of Applied Sciences Upper Austria, Hagenberg Campus, Bioinformatics Research Group, Softwarepark 13, Hagenberg, Austria; Red Cross Transfusion Service of Upper Austria, Linz, Austria; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria; Elisabethinen Hospital, Linz, Austria; Medical University of Vienna, Department of Nephrology, Vienna, Austria

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