IMID specifications


Unique identifier OMICS_02705
Alternative name Integrated Molecular Interaction Database
Restrictions to use None
Maintained Yes

Publication for Integrated Molecular Interaction Database

IMID citations


Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon‐independent manner

Mol Oncol
PMCID: 5792743
PMID: 29130642
DOI: 10.1002/1878-0261.12157

[…] Using AcceSssIble, we were able to compare the combined chromatin accessibility and methylation changes between IMiD‐sensitive cell lines for a total of 522 554 probes across the genome. Interestingly, we found that acquired resistance for both lenalidomide and pomalidomide in OPM2 was primarily associated with […]


Leveraging the new with the old: providing a framework for the integration of historic microarray studies with next generation sequencing

BMC Bioinformatics
PMCID: 4251047
PMID: 25350881
DOI: 10.1186/1471-2105-15-S11-S3

[…] ling studies used in the various analyses are presented in Figure . Although the outcomes for MM patients have considerably improved, those who are refractory to, or relapse following therapy with an IMiD and/or proteasome inhibitor have a poor prognosis []. NGS sequencing of MM patients have revealed multiple targetable mutations, including KRAS [,].Figure shows the system rendered results of th […]

IMID institution(s)
Department of Statistics, Florida State University, Tallahassee, FL, USA

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