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ImmuNet specifications


Unique identifier OMICS_23341
Name ImmuNet
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Olga G. Troyanskaya
  • person_outline Stuart Sealfon

Additional information

Publication for ImmuNet

ImmuNet citations


System analysis of the regulation of the immune response by CD147 and FOXC1 in cancer cell lines

PMCID: 5849184
PMID: 29560120
DOI: 10.18632/oncotarget.24161

[…] tive regulator for immune response processes (Figure ). To evaluate the reproducibility, we also compiled a list of 796 genes as Immu_Genes from 15 expert-curated KEGG immune-related pathways ( [] (). The results were highly concordant across the two lists of Immu_Genes from different sources, which independently validated the strong negative correlation between the […]


Multiple network constrained regressions expand insights into influenza vaccination responses

PMCID: 5870750
PMID: 28881994
DOI: 10.1093/bioinformatics/btx260

[…] of genes within each gene set. The KEGG network incorporated pathway topology and was built using the KEGGgraph R package v1.26.0 (). ImmuneGlobal and ExpOnly_ImmuneGlobal networks were obtained from ImmuNet and edges were restricted to those with confidence of at least 0.1 (). The STRING network incorporated all experimental evidence from the STRING database v10.0. The processed LINCS L1000 gene […]


Proteomics and integrative omic approaches for understanding host–pathogen interactions and infectious diseases

Mol Syst Biol
PMCID: 5371729
PMID: 28348067
DOI: 10.15252/msb.20167062

[…] on information (Jean Beltran et al, ). An important aspect of multi‐omics studies is the availability of informatics platforms that can be used to access and visualize the data. Some examples include ImmuNet (Gorenshteyn et al, ), a tool that integrates immune pathway knowledge and omics data, and ZikaVR (Gupta et al, ), a tool for visualization of multi‐omic data from Zika virus research. The ava […]


Novel Monoclonal Antibody and Peptide Binders for Mycobacterium avium subsp. paratuberculosis and Their Application for Magnetic Separation

PLoS One
PMCID: 4729677
PMID: 26815790
DOI: 10.1371/journal.pone.0147870

[…] ese peptide sequences had previously been identified as binding to unrelated target sequences or as plastic binders [], each of the sequences were also scanned through the online SAROTUP tool (, []).Following DNA sequencing, phage expressing different peptide sequences were individually amplified in E. coli ER2738 and assessed for their ability to bind MAP B4 ce […]


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ImmuNet institution(s)
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; New York Genome Center, New York, NY, USA; Simons Center for Data Analysis, Simons Foundation, New York, NY, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Departments of Pathology and Immunobiology, Yale School of Medicine, New Haven, CT, USA; Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA; Department of Computer Science, Princeton University, Princeton, NJ, USA
ImmuNet funding source(s)
Supported by NIH Contract HHSN272201000054C and Grant 1U19AI117873; by a Senior Fellow of CIFAR and by T32 MH096678.

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