A convenient web based application for analyzing next-generation sequencing results and reporting IGH gene rearrangements for both repertoire and clonality studies. IGGalaxy has two analysis options one using the built in igBLAST algorithm and the second using output from IMGT; in either case repertoire summaries for the B-cell populations tested are available. IGGalaxy supports multi-sample and multi-replicate input analysis for both igBLAST and IMGT/HIGHV-QUEST. IGGalaxy is built on top of the Galaxy framework (http://galaxyproject.org/) and is distributed as a virtual machine image.

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IGGalaxy classification

IGGalaxy specifications

Software type:
Restrictions to use:
Programming languages:
Perl, Python, R
Web user interface
Biological technology:
Illumina, Roche
Computer skills:



  • (Moorhouse et al., 2014) ImmunoGlobulin galaxy (IGGalaxy) for simple determination and quantitation of immunoglobulin heavy chain rearrangements from NGS. BMC immunology.
    PMID: 25495099


Department of Bioinformatics, Erasmus University Medical Center, Rotterdam, The Netherlands

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