ImOSM specifications


Unique identifier OMICS_33017
Name ImOSM
Alternative name Imbedding One Step Mutations
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages C++
Computer skills Advanced
Stability Stable
Source code URL
Maintained Yes




No version available



  • person_outline Arndt von Haeseler
  • person_outline Minh Anh Thi Nguyen

Publication for Imbedding One Step Mutations

ImOSM citations


Robust circadian clock oscillation and osmotic rhythms in inner medulla reflecting cortico medullary osmotic gradient rhythm in rodent kidney

Sci Rep
PMCID: 5544761
PMID: 28779094
DOI: 10.1038/s41598-017-07767-8

[…] qp2, V1aR, and V2R showed no significant rhythms in Bmal1 deficient mice (Fig. ).Figure 4 In wild type mice, osmotic pressure in the IM at ZT16 was 1.42 times higher than that at ZT4 (p = 0.027), and IMosm/cortosm value reflecting osmotic pressure gradient at ZT16 was 1.40 times higher than that at ZT4 (p = 0.027) (Fig. ). These results are similar to day-night variations in rat kidneys (Fig. ). A […]


ImOSM: Intermittent Evolution and Robustness of Phylogenetic Methods

Mol Biol Evol
PMCID: 3258038
PMID: 21940641
DOI: 10.1093/molbev/msr220
call_split See protocol

[…] Assume that we have a phylogenetic tree 𝒯 and an alignment 𝒜 that evolved along 𝒯 under a model of sequence evolution ℳ. ImOSM introduces extra substitutions that occur somewhere on 𝒯, thus changing the alignment 𝒜, which otherwise perfectly fits the substitution process defined by ℳ. To this end, we utilize the concept […]

ImOSM institution(s)
Center for Integrative Bioinformatics Vienna, Max F. Perutz Laboratories, University of Vienna, Medical University of Vienna, University of Veterinary Medicine Vienna, Vienna, Austria
ImOSM funding source(s)
Supported by the Wiener Wissenschafts-, Forschungs- and Technologiefonds, the DFG Deep Metazoan Phylogeny project, SPP (HA1628/9), and the Genome Research in Austria project Bioinformatics Integration Network III.

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