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ImpG-Summary specifications

Information


Unique identifier OMICS_07885
Name ImpG-Summary
Software type Package/Module
Interface Command line interface
Restrictions to use Academic or non-commercial use
Input data ImpG-Summary takes as input 1000 Genomes reference haplotypes and summary association statistics at a typed set of SNPs from a GWAS or meta-analysis.
Output data It outputs summary association statistics at all 1000 Genomes variants.
Operating system Unix/Linux
Computer skills Advanced
Version 1.0
Stability Stable
Maintained Yes

Versioning


No version available

Maintainer


  • person_outline Bogdan Pasaniuc

Publication for ImpG-Summary

ImpG-Summary citations

 (2)
library_books

Identification of shared risk loci and pathways for bipolar disorder and schizophrenia

2017
PLoS One
PMCID: 5293228
PMID: 28166306
DOI: 10.1371/journal.pone.0171595

[…] project, february 2012 release; and hapmap phase 2 ceu, respectively). therefore, the summary statistics of the pgc bd gwas [] were imputed using the 1,000 genomes project reference panel and impg-summary. the latter is a recently proposed method for the rapid and accurate imputation of summary statistics []. this resulted in z-scores for >20 million snps. a total of 111 scz-associated […]

library_books

Bias Characterization in Probabilistic Genotype Data and Improved Signal Detection with Multiple Imputation

2016
PLoS Genet
PMCID: 4910998
PMID: 27310603
DOI: 10.1371/journal.pgen.1006091

[…] suitability of mi to a given application is restricted to situations where the probability-generating method is itself appropriately suited., recent work ([–]) has produced algorithms (mix, distmix, impg-summary) capable of imputing association statistics from summary data, without the need for individual-level genotype information. these methods offer substantial time savings relative […]


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ImpG-Summary institution(s)
Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, CA, USA

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