IMPre statistics

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Citations per year

Number of citations per year for the bioinformatics software tool IMPre

Tool usage distribution map

This map represents all the scientific publications referring to IMPre per scientific context
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Associated diseases


Popular tool citations

chevron_left Bioinformatics workflows Germline reconstruction chevron_right
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IMPre specifications


Unique identifier OMICS_19163
Name IMPre
Alternative name Immune Germline Prediction
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages C, Perl
License GNU General Public License version 3.0
Computer skills Advanced
Version 1..1.0
Maintained Yes


No version available


  • person_outline Xiao Liu

Publication for Immune Germline Prediction

IMPre citations


Analyzing Immunoglobulin Repertoires

Front Immunol
PMCID: 5861150
PMID: 29593723
DOI: 10.3389/fimmu.2018.00462

[…] umans and mice have the most well defined Ig gene loci, but a map of all allelic variants is not complete (). There have been efforts to address this with algorithms—such as TIgGER (), IgDiscover (), IMPre (), and a more recent allele prediction and validation tool ()—that can be used to identify germline alleles for individual repertoires. Proper identification of non-template additions and delet […]


Next Generation Sequencing of Antibody Display Repertoires

Front Immunol
PMCID: 5810246
PMID: 29472918
DOI: 10.3389/fimmu.2018.00118

[…] rogram such as PEAR (). Separate analysis of heavy and light chains may be required for antibody formats such as scFv, where the presence of synthetic linkers can complicate analyses.Programs such as IMPre (), IgBLAST (), IMGT/High V-QUEST (, ), and ImmundiveRsity (), which were originally developed for the analysis of B and T cell receptor repertoires, identify VH and VL germlines as well as VH a […]


Combined Characterization of the Time Response of Impression Materials via Traditional and FTIR Measurements

PMCID: 5455552
DOI: 10.3390/ma8052387

[…] , described by the manufacturer as “advance termasense” formulation []. Obviously, an increase in temperature activates an increase of viscosity for Flexi and slows down the increase of viscosity for Impre. Additionally, Impre values at BT are shifted to higher values than for the corresponding datapoints of the same material at RT, at all times, and also versus all the other materials, which mean […]


Genomic Divergence during Speciation Driven by Adaptation to Altitude

Mol Biol Evol
PMCID: 3840311
PMID: 24077768
DOI: 10.1093/molbev/mst168

[…] t SNP data to the format suitable for use in the dadi package.We tried several demographic scenarios implemented in dadi and focused on the isolation-with-migration model with population size change (IMpre). The parameters of the model are described in the Results, and the most likely inferred scenario for this model is shown in . This model was fit to our data with all eight parameters (Tb, Nb, s […]


A New Paradigm for MAPK: Structural Interactions of hERK1 with Mitochondria in HeLa Cells

PLoS One
PMCID: 2760858
PMID: 19847302
DOI: 10.1371/journal.pone.0007541

[…] the interaction was performed with cells transfected with GFP and further labelled against histones or VDAC and the Cy3 secondary antibody as above. The FRET efficiency (FRET) was determined as:where Impre and Impos were GFP images before and after Cy3 photobleaching.Other images were acquired with an Olympus FV-1000 confocal microscope using a 60×1.35 NA oil immersion objective. Excitation and fi […]

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IMPre institution(s)
Beijing Genomics Institute (BGI-Shenzhen), Shenzhen, China; Merck Research Laboratories, West Point, PA, USA
IMPre funding source(s)
Supported by the Beijing Genomics Institute.

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